the effect serum vitamin d normalization in preventing recurrences of benign paroxysmal positional vertigo .a case-control study

نویسندگان

mahboobeh sheikhzadeh department of audiology, university of social welfare and rehabilitation sciences, tehran, iran.

yones lotfi department of audiology, university of social welfare and rehabilitation sciences, tehran, iran.

abdollah mousavi department of audiology, university of social welfare and rehabilitation sciences, tehran, iran.

behzad heidari ganjafrooz street, babol university of medical science, iran

چکیده

background: benign paroxysmal positional vertigo (bppv) is a condition with recurrent attacks in a significant proportion of patients. the present case- control study was conducted to assess the influence of serum vitamin d normalization on recurrent attacks of vitamin d deficient patients. methods: diagnosis of bppv was made based on history and clinical examination and exclusion of other conditions. serum 25-hydroxy vitamin d (25-ohd) was measured using elisa method and a levels of < 20 ng/ml was considered a deficiency of vitamin d. inclusion criteria were as follows: history of recurrent attacks and serum 25-ohd<20.ng/ml. while the patients with history of trauma, surgery and chronic systemic diseases were excluded. the patients were classified into two groups: treatment and control, intermittently. both groups received epley rehabilitation therapy one session per week for 4 weeks but the treatment group received an additional supplement of 50.000 iu of vitamin d (cholecalciferol) weekly for two months to achieve serum 25-ohd ≥ 30 ng/ml and the study patients were followed-up for 6 months. results: twenty-seven patients were allocated to each group. at baseline, serum 25-ohd was similar (10.7±2.3 vs 11.41±1.9, p=0.23). at month 2, serum 25-ohd in the treatment group increased significantly to ≥ 30 ng/ ml, whereas serum 25-ohd in the control group remained unchanged (34.2±3.3 vs 10.6 10.6±2.2 ng/ml, p=0.001). during the follow-up period, attacks of bppv in the treatment group decreased significantly compared with the control group (14.8% vs 96.3% or= 0.18, p=0.001). conclusion: the findings of this study indicate that the normalization of serum vitamin d significantly reduces bppv recurrences.

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The effect serum vitamin D normalization in preventing recurrences of benign paroxysmal positional vertigo .a case-control study

Background: Benign paroxysmal positional vertigo (BPPV) is a condition with recurrent attacks in a significant proportion of patients. The present case- control study was conducted to assess the influence of serum vitamin D normalization on recurrent attacks of vitamin D deficient patients. Methods: Diagnosis of BPPV was made based on history and clinical examination and exclusion of other c...

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عنوان ژورنال:
caspian journal of internal medicine

جلد ۷، شماره ۳، صفحات ۱۷۳-۱۷۷

کلمات کلیدی
[ ' b p p v ' , 2 5 , ' h y d r o x y v i t a m i n d ' , ' e p l e y t h e r a p y ' , ' r e c u r r e n t v e r t i g o ' ]

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